Search results for "Cardioplegic Solutions"

showing 3 items of 3 documents

A New Technical Approach For Retrograde Administration of Cardioplegic Solutions

1989

Myocardial protection via the coronary sinus is now currently used by several groups. Although it has generally provided satisfactory results, some of its problems are still not completely resolved. We present a new technique of cardioplegia delivery through the coronary sinus with a Pezzer catheter inserted into it and secured in place by a purse string suture. We believe that this method is safer and more reliable than others.

Pulmonary and Respiratory MedicinePurse string sutureCardiac CatheterizationCardiopulmonary Bypassbusiness.industryCoronary DiseaseCardioplegic solutionsCoronary diseaselaw.inventionCatheterlawAnesthesiaHeart catheterizationHeart Arrest InducedCardiopulmonary bypassHumansMedicineSurgeryCardiology and Cardiovascular MedicinebusinessCardioplegic SolutionsCoronary sinusThe Thoracic and Cardiovascular Surgeon
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Isolated in-vitro perfusion of pig hearts obtained from the abattoir: an alternative to animal experiments?

1994

Isolated pig hearts (German farm pigs) were characterized after global in-vivo ischaemia as a potential alternative to in-vivo animal studies. Hearts were harvested from adult farm swine at the abattoir 10.3 +/- 2.1 min after incision of the carotid artery. They were immediately perfused and thereafter stored in ice-cold cardioplegic (St Thomas's) solution. After 38 +/- 3 min, retrograde perfusion was started with oxygenated pig blood (37 degrees C; 5000 U Heparin.l-1; pH 7.38 +/- 0.1; 11 mmol glucose.l-1) at a flow rate of 85 ml.min-1 100 g-1 wet weight (gww-1) for 30 min (n = 10). Additionally, shortly after obtaining the hearts, ATP and CP content were measured by enzymatic tests in 10 p…

SwineSodiumCarotid arterieschemistry.chemical_elementMyocardial Reperfusion InjuryCalciumIn Vitro TechniquesSodium ChlorideAnimal Testing AlternativesPotassium ChlorideAndrologyCalcium ChlorideReperfusion therapyHeart rateRetrograde perfusionMedicineAnimalsMagnesiumCardioplegic SolutionsMyocardial Stunningbusiness.industryMagnesiumMyocardiumHeartAnatomyPerfusionBicarbonateschemistryCardiology and Cardiovascular MedicinebusinessPerfusionAbattoirsEuropean heart journal
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Myocardial Protection by Retrograde Cardioplegic Perfusion in the Presence of Acute Coronary Artery Obstruction: An Experimental Study

1992

To investigate retrograde delivery of cardioplegic solutions as a means of enhancing myocardial protection in the presence of coronary artery occlusion, a two-part experimental model was devised. In part 1 (in vitro) the possibility of retroperfusing the entire myocardium during acute occlusion of the left anterior descending artery (LAD) was assessed. In part 2 (in vivo) acute LAD occlusion was performed in dogs, and during 2 hours of aortic cross-clamping crystalline cardioplegic solution was infused at 20-minute intervals. In group I the infusion was antegrade, via the aortic root, and in group II it was retrograde, via the coronary sinus. Thereafter the LAD snare was released and the do…

medicine.medical_specialtyGroup iiContrast MediaBlood PressureCoronary DiseaseCoronary AngiographyPotassium ChlorideDogsBody WaterHypothermia InducedInternal medicineOcclusionmedicineCarnivoraAnimalscardiovascular diseasesCardioplegic SolutionsAortaCoronary sinusCardioprotectionCardiopulmonary Bypassbiologybusiness.industryMyocardiumFissipediaHeartbiology.organism_classificationCoronary VesselsPerfusionmedicine.anatomical_structureAnesthesiaHeart Arrest Inducedcardiovascular systemCardiologyCardiology and Cardiovascular MedicinebusinessPerfusionArteryScandinavian Journal of Thoracic and Cardiovascular Surgery
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